As part of the ADVISAR project, the effects of emissions from aircraft turbines are being comprehensively investigated from a chemical and physical perspective. In collaboration between Zurich University of Applied Sciences and Adolphe Merkle Institute, human lung cell cultures are now being exposed to diluted aircraft emissions from the engine test cell at SR Technics. […]
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First studies using our Cloud systems have already been successfully published (see link in the comments). Another widespread challenge is dry eye disease, where further studies are needed – and there’s a lot happening in the Eye-on-a-Chip community! For these applications, ultra-thin porous membranes, tunable mechanical properties, and compatibility with multiple readouts are key. For […]
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Vitrocell exposure systems enable direct air–liquid interface (ALI) exposure of mammalian cells and tissues to real-world airborne substances. From gases, complex mixtures, and combustion exhausts to cigarette smoke, e-cigarette vapor, household chemicals, nanomaterials, pharmaceutical aerosols, dry powders, and even viruses, Vitrocell supports high-quality in vitro inhalation research. Vitrocell helps teams generate reliable, reproducible data for […]
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In traditional submerged cell culture, airway cells are covered by liquid – a condition that does not reflect how humans actually breathe. At the Air–Liquid Interface (ALI), mammalian cells and tissues are exposed directly to airborne substances, replicating human respiratory physiology more closely and producing more predictive, human-relevant results. From toxicology to pharmaceutical development and […]
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Not all test atmospheres can be tested the same way. Some require the Continuous Flow Exposure Principle. In our Continuous Flow Exposure Systems, mammalian cells, tissues, and ex vivo material can be exposed to a constant flow of gases, complex mixtures, or particles – allowing both gas and particle phases to be assessed simultaneously. Furthermore, […]
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Following successful factory acceptance testing at Vitrocell in Waldkirch, we recently completed the final user training for the AirTox Monitor systems at LISA – Laboratoire Interuniversitaire des Systèmes Atmosphériques, (Université Paris Cité/Université Paris-Est Créteil (UPEC)/CNRS, France). What often matters most at this stage is not the system itself – but how confidently research teams can […]
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In a recently published study, researchers from the Institut de Recherche Biomédical des Armées (IRBA) and INERIS carried out repeated, sub-lethal co-exposures to aluminum oxide nanoparticles (Al₂O₃ NPs) and hydrogen chloride (HCl). A human air–liquid interface co-culture model of alveolar epithelial cells and fibroblasts was exposed using the VITROCELL Cloud System. Key findings: No loss […]
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Only when output rates are well controlled can we ensure that the same amount of aerosol reaches all positions in the system, enabling homogeneous deposition and robust, reproducible exposure conditions. To support this, our systems are equipped with an internal logger that tracks nebulizer performance over time. This allows users to monitor nebulizer condition throughout its […]
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Single Droplet Sedimentation Systems are designed for dose-controlled, spatially uniform deposition of liquid aerosols at the Air–Liquid Interface. This exposure principle is ideal when: you work with liquid samples or suspensions materials are scarce or highly valuable precise dose control is required short, repeatable exposures are sufficient Aerosols are generated from small solution or suspension […]
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The U.S. The National Institutes of Health (NIH) has announced an investment of more than $150 million to advance human‑based research methods and reduce reliance on animal models. This funding represents the first awards under the Complement Animal Research in Experimentation (Complement‑ARIE) program, focused on developing, validating, and standardizing new approach methodologies (NAMs) — including advanced in vitro and […]
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